Method development for the analysis of 1,4-dioxane in drinking water using solid-phase extraction and gas chromatography-mass spectrometry.
نویسندگان
چکیده
1,4-Dioxane has been identified as a probable human carcinogen and an emerging contaminant in drinking water. The United States Environmental Protection Agency's (U.S. EPA) National Exposure Research Laboratory (NERL) has developed a method for the analysis of 1,4-dioxane in drinking water at ng/L concentrations. The method consists of an activated carbon solid-phase extraction of 500-mL or 100-mL water samples using dichloromethane as the elution solvent. The extracts are analyzed by gas chromatography-mass spectrometry (GC-MS) in selected ion monitoring (SIM) mode. In the NERL laboratory, recovery of 1,4-dioxane ranged from 94-110% in fortified laboratory reagent water and recoveries of 96-102% were demonstrated for fortified drinking water samples. The relative standard deviations for replicate analyses were less than 6% at concentrations exceeding the minimum reporting level.
منابع مشابه
Determination of 1,4-dioxane in Drinking Water by Solid Phase Extraction (spe) and Gas Chromatography/ Mass Spectrometry (gc/ms) with Selected Ion
متن کامل
Combined Determination of 1,4-Dioxane and Nitrosamine Contaminants in Drinking Water Using SPE and CSR-LVSI GC-MS
Global concern over the carcinogenic potential of 1,4-dioxane and several nitrosamines has resulted in increased interest in the development of more efficient testing methods for these contaminants in drinking waters. In the U.S., the current methodologies recommended for the analysis of 1,4-dioxane and nitrosamines in drinking waters are Environmental Protection Agency (EPA) Methods 522 and 52...
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Global concern over the carcinogenic potential of 1,4-dioxane and several nitrosamines has resulted in increased interest in the development of more e" cient testing methods for these contaminants in drinking waters. In the U.S., the current methodologies recommended for the analysis of 1,4-dioxane and nitrosamines in drinking waters are Environmental Protection Agency (EPA) Methods 522 and 521...
متن کاملDetermination of 1,4-dioxane in Drinking Water by Solid Phase Extraction (spe) and Gas Chromatography/mass Spectrometry (gc/ms) with Selected Ion Monitoring (sim)
متن کامل
The extraction and analysis of 1,4-dioxane from water using solid-phase microextraction coupled with gas chromatography and gas chromatography-mass spectrometry.
In this study, two methods are developed for the extraction of 1,4-dioxane (dioxane) from water using 80-microm carboxen-polydimethylsiloxane solid-phase microextraction fibers followed by either gas chromatography (GC)-flame ionization detection (FID) or GC-mass spectrometry (MS). With GC-FID, the lower limit of detection (LOD) for 1,4-dioxane is 2.5 microg/L (ppb) with a linear range of 5 to ...
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ورودعنوان ژورنال:
- Journal of chromatographic science
دوره 47 1 شماره
صفحات -
تاریخ انتشار 2009